Urinary incontinence is a condition, in which there is an involuntary leakage of urine, which adversely affects the quality of life. According to domestic research, 36% to 45% of women report symptoms of involuntary urination. Globally, more than 200 million women suffer from urinary incontinence.
- Stress urinary incontinence (occurs in 49% of cases) – is the involuntary leakage of urine when coughing, laughing, running and other physical activities that increase intra-abdominal and therefore intravesical pressure. A characteristic feature of stress urinary incontinence is a lack of urge to urinate.
- Urge (found in 22% of cases) – is the involuntary leakage of urine that occurs immediately after a sharp urge to urinate, but sometimes urine leakage occurs almost suddenly, with a very short preceding period of urge.
- Mixed urinary incontinence (occurs in about 29% of cases) is typical of older women. In this case, patients complain of urinary leakage, which precedes urge, the uncontrollable urge to urinate, or incontinence occurring in the absence of urge after a significant physical exertion.
Currently, there are three main methods for the treatment of urinary incontinence:
- Drug-free treatment method – bladder holding training, exercises for pelvic muscles and physiotherapy.
- Medical (treatment with medication: antispasmodics and antidepressants)
- Surgical (sling operations for example)
Although many women with urinary incontinence achieve good results with the application of medical methods of treatment, some doctors find it necessary to use surgical methods. The choice of surgical treatment is determined by the effectiveness of prior urinary incontinence non-surgical treatment modalities. Effective methods for treating urinary incontinence such as free synthetic loops have been used since 1996. This so-called sling operation reduces the duration of the operation and surgical trauma. There are more than 200 surgical treatment techniques for stress urinary incontinence; plastic correction of the bladder sphincter, bladder neck strengthening and more. The success of these operations is between 70 to 90%.
A promising direction is the use of biomaterials that can be used in sling operations, as the use of synthetic materials can cause various complications (infectious and inflammatory processes, erosion, etc.) Use of collagen for the treatment of urinary incontinence has become widely popular due to the security, reliability and efficiency derived from the results of its application. The percentage of successful application of collagen varies from 88 to 100%.
A number of successful pilot studies on the use of the collagen material Salvecoll® as a material for sling operations have been carried out. On that basis Salvecoll® is considered a promising material for use in women with stress incontinence.