Trophic Ulcer, Diabetic Foot Syndrome, and Pressure sores
Application of Salvecoll® for the treatment of trophic ulcers, diabetic foot syndrome, and pressure sores can help heal wounds of varying depth and complexity, as well as long-term non-healing wounds. Salvecoll® stimulates the body into performing correct natural healing processes. Due to the natural preserved structure of its collagen fibers, Salvecoll® facilitates the rapid and efficient growth of new high-grade tissue in place of the defect. Salvecoll® itself acts as a template for the growth of new tissue: fibroblasts, blood vessels and lymphatic vessels, nerve fibers from the surrounding healthy tissue, penetrate into the collagen matrix, and are distributed strictly thereon. During the healing process Salvecoll® is gradually absorbed, creating new high-grade tissue. Salvecoll® prevents the overgrowth of granulation and scar tissue, thereby preventing the formation of a scar. Thus, Salvecoll® is effective for the treatment of trophic ulcers, as it significantly speeds up the healing process and leads to the formation of high-grade epithelial tissue, which makes therapy with Salvecoll® a unique method for trophic ulcer treatment.
- Reduces wound inflammation and prevents the loss of fluid, thereby creating the necessary moist environment for healing
- Helps cleanse the wound
- Acts as a barrier against secondary infections
- Becomes a matrix on which the growth of new collagen fibers are strictly directed, resulting in a complete tissue regeneration
- In place of Salvecoll® gel injection or implants, collagen fibers begin to form on their own and Salvecoll® gradually biodegrades.
- At the site of the healed wound complete, tissue is formed that is similar in structure to the surrounding healthy tissue
Treatment with Salvecoll® is an effective method for the treatment of trophic ulcers using a variety of Salvecoll® dosage forms.
An allergic test sample (the physician inserts 0.1 ml of gel Salvecoll® into the skin of the forearm) can be performed at the discretion of the physician in order to avoid an allergic reaction.
- The physician performs primary surgical treatment of the wound
- Salvecoll® membrane is soaked in a 0.9% solution of NaCl (or in an antiseptic or antibiotic solution), and cut to the size of the wound
- To properly seal the defected area, one or more Salvecoll® membranes may be required.
- For optimal results, the physician may also use Salvecoll® gel for filling around the perimeter of the wound
- On top of the Salvecoll® membrane the wound is closed with a bandage or sterile gauze soaked in 0.9% solution of NaCl. As the bandage dries it is moistened and fixed to the surrounding skin
- Active dressings are changed once every 5-7 days until the wound has completely healed
- Salvecoll® reduces healing time by a factor of 1.5-2
- Salvecoll® is shown to cure ulcers that were previously resistant to treatment
- Significant decrease in pain and inflammation is observed
- The treatment results in formation of complete tissue similar in structure to the healthy tissue surrounding the wound
- Wound dressings are done once every 5-7 days
- Relapse after treatment with Salvecoll® is not observed
Patient: Female, 38 years old
Diagnosis: Trophic ulcer on the front surface of the middle third of the left tibia, which developed after an injury sustained 8 months previous. Repeatedly treated in inpatient care without results. Underwent outpatient treatment with Salvecoll®. Comorbidities: CVI (CEAP C6), pituitary adenoma.
Patient: Female, 54 years old
Diagnosis: Semi-circular trophic ulcer on the lower third of the right lower leg for 2 years. Treated in inpatient care. Four operations conducted: autodermoplasty free split-skin grafting. Comorbidities: CVI (CEAP C6), type 2 diabetes.
Patient: Male, 45 years old
Diagnosis: In anamnesis – scalp wound (3.5 years old). Repeated attempts at autodermoplasty failed. Related diagnosis of type 2 diabetes, requires insulin, subcompensated, moderate severity.
Patient: Male, 62 years old
Diagnosis: Non-healing wound on the right shin. Also diagnosed with high severity diabetes mellitus type II, sub-compensated; CVI III (CEAP C6), PTS.
Patient: Girl, 3 years and 11 months old
Diagnosis: Necrotic deep open wound on the inner surface of the right ankle and right foot.
Patient: Male, 46 years old
Diagnosis: Diabetic foot, trophic non-healing ulcer on the left foot and left shin. Diabetic angiopathy of the lower extremities.
